Sound science must be our guide in choosing which problems to tackle and how to approach them.

It is our job above all in politics to tackle the big issues and to explain them and have the honesty to say to people 'There are no easy solutions here.'

Broadcasters or politicians or writers who think that they are respecting Struggle Street the battlers by dumbing things down into one-line sound bites are not respecting them they are treating them with contempt. It's our job above all in politics to tackle the big issues and to explain them.

For a successful entrepreneur it can mean extreme wealth. But with extreme wealth comes extreme responsibility. And the responsibility for me is to invest in creating new businesses create jobs employ people and to put money aside to tackle issues where we can make a difference.

I got tackled once in a movie theater. I was with my mom and brother and then suddenly I got hit from behind and sort of sprawled out on the candy counter.

This is a historic moment in global public health demonstrating the international will to tackle a threat to health head on.

It's time to look beyond the budget ax to assure access to health care for all. It's time to look for bipartisan solutions to the problems we can tackle today and to work together for tomorrow - building a health care system that works for all Americans.

One lion thinks it's just hilarious to tackle us. He's very funny about it... and we always know when it will happen.

Outside of the chair the teapot is the most ubiquitous and important design element in the domestic environment and almost everyone who has tackled the world of design has ended up designing one.

My message to you all is of hope courage and confidence. Let us mobilize all our resources in a systematic and organized way and tackle the grave issues that confront us with grim determination and discipline worthy of a great nation.