I'm not a movie guy I'm not a TV sitcom guy but whatever seems to fit and is funny is good for me.
The reason why you know more funny dudes than funny chicks is that dudes are funnier than chicks. If my daughter has a mediocre sense of humor I'm just gonna tell her 'Be a staff writer for a sitcom. Because they'll have to hire you they can't really fire you and you don't have to produce that much. It'll be awesome.'
The humor is essentially dark for a cartoon and sophisticated. But at the same time being a cartoon gives the writers more freedom than in a normal sitcom. It always pushes the line that despite human failings the Simpsons are really decent people.
A lot of times I would go into a room and audition for whatever sitcom it was and they would expect me to do sort of what my dad was doing and I am not him so they would be disappointed and I would feel nervous and not know exactly how to do it.
Basically after an ABC sitcom I did I ended up with a holding deal with 20th Century Fox. Absolutely cool. It pays you to be unemployed. And the bigger the entity that gives you the deal the better.