In the history of the treatment of depression there was the dunking stool purging of the bowels of black bile hoses attempts to shock the patient. All of these represent hatred or aggression towards what depression represents in the patient.
I always thought it was strange when these artists like Kurt Cobain or whoever would get really famous and say 'I don't understand why this is happening to me.' There is a mathematical formula to why you got famous. It isn't some magical thing that just started happening.