The ever quickening advances of science made possible by the success of the Human Genome Project will also soon let us see the essences of mental disease. Only after we understand them at the genetic level can we rationally seek out appropriate therapies for such illnesses as schizophrenia and bipolar disease.

It's rather splendid to think of all those great men and women who appear to have presented symptoms that allow us to describe them as bipolar. Whether it's Hemingway Van Gogh... Robert Schumann has been mentioned... Virginia Woolf Sylvia Plath... some of them with rather grim ends.