I think that different pleasures work for different readers - a friend of mine won't read anything that's not a cardiovascular sort of page-turner. I tend to care less about plot but I'm a sucker for humor and strangeness.
A permanent base on Mars would have a number of advantages beyond being a bonanza for planetary science and geology. If as some evidence suggests exotic micro-organisms have arisen independently of terrestrial life studying them could revolutionise biology medicine and biotechnology.